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DMF induces the expression of L-2-hydroxyglutarate dehydrogenase (L2HGDH) to downregulate L-2-hydroxyglutarate (L2HG) and increase global and locus-specific DNA hydroxymethylation levels

Blood 93(5):1668-76, 1999

Park, S.-H

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This assumption is supported by the finding that only the overexpression of GCL, and not of GS, results in increased GSH levels ( The second pathway of GSH synthesis is that related to the recycling of cysteine