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B12 Injections and Weight Loss The idea of B12 shots leading to weight loss probably came from the observational studies that linked low vitamin B12 to a higher body-weight: Low vitamin B12 level was associated with obesity and overweight, but not with insulin resistance, metabolic syndrome and gender

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Less Common / Possible Effects Digestive upset (oral/troche forms): Some compounded non-injectable versions may cause mild gastrointestinal discomfort

The gauge of the needle refers to its thickness

however, only 50% of all individuals in the general population with these antibodies have pernicious anemia