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Phylum-level analyses indicate predominant Firmicutes with relative Bacteroidetes reduction in some studies (264, 265), while others report increased Actinobacteria , Verrucomicrobia , or pro-inflammatory Proteobacteria , alongside potential reduction of beneficial Bacteroidetes and Actinobacteria ( 262, 266)

However, this represents a functional adaptation rather than true anatomical shrinkage and would likely reverse if eating patterns returned to baseline after medication discontinuation

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A few times, they didnt come back

Its role is particularly important in protecting cells from oxidative stress, assisting in immune responses and supporting overall metabolic health