Senotherapeutics to counteract senescent cells are prominent topics in the context of anti-aging strategies
186 In fact, increased levels of cysteinyl-s-conjugates in biological fluids have been associated with several cancers, including melanoma, non-Hodgkin lymphoma, breast, ovarian and thyroid carcinomas, and with poor prognosis, recurrence and survival (see below)
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BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a protective protein found naturally in human gastric juice
765 In addition, caffeic acid, 766 -caryophyllene, 767 15, 16-dihydrotanshinone, 768 icariside II, 769 rehmannioside A, 770 kaempferol, 771 rhein, 772 loureirin C, 773 quercetin, 774 and kellerin 775 suppress ferroptosis induced by cerebral I/R injury by activating the Nrf2 signaling pathway, which further suggests that activating the Nrf2 signaling pathway may be a potential treatment for relieving cerebral I/R injury
