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We felt it was important to document her clinical course to inform clinicians facing similarly complex patients. Indeed, children with early-onset obesity develop insulin resistance, liver dysfunction, and beta cell decline much more rapidly than adults because their organs and metabolic systems are developing, which makes them more vulnerable to the harmful effects of excess adiposity

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They attract immune and repair cells to the area and promote angiogenesis, the formation of new blood vessels that supply essential nutrients and oxygen to healing tissue