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Briefly, FLS were transfected with 100 nM AMPK siRNA (Genepharma, Shanghai, China), 100 nM CPT1 siRNA, or scrambled siRNA (sc-156134 and sc-37007

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As the race for the next "blockbuster pill" intensifies, R&D teams are under pressure to identify "me-too" or "me-better" scaffolds while avoiding Eli Lillys massive patent thicket