Shop Medications , Manufacturer Recommendations Eli Lilly advises that when you start tirzepatide or after any dose escalation, you should: Continue your oral contraceptive Add a barrier method (for example, condoms) for 4 weeks Or switch to a nonoral method (IUD, vaginal ring, implant) before starting tirzepatide if you prefer not to use a barrier method How Tirzepatide Affects Oral Contraceptives Tirzepatide is a dual agonist of GLP-1 and GIP receptors
Ziegler D, Ametov A, Barinov A, Dyck PJ, Gurieva I, Low PA, Munzel U, Yakhno N, Raz I, Novosadova M, Maus J
What Standard Tests Miss Most gut tests use 16S rRNA sequencing, which only assesses bacteria
Based on the trial population and clinical reasoning: - Adults with BMI 30+ who have not achieved goals with [semaglutide or tirzepatide](/guides/retatrutide-vs-semaglutide-comparison-guide) - Patients who plateaued on existing incretin therapy and need additional efficacy - Individuals with significant metabolic dysfunction (insulin resistance, fatty liver, metabolic syndrome) - Those whose healthcare provider has experience with peptide therapeutics **Not appropriate for:** Pregnant or nursing women, individuals with MTC/MEN2 family history, active pancreatitis, or anyone without medical supervision
Contrave Contrave comes in tablet form, so its great for those who hate injections, and has two active ingredients: bupropion and naltrexone