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The difference may partly reflect dose equivalency issues in trials rather than a true pharmacological difference

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To further elucidate the therapeutic mechanisms underlying D-CuPs multivalent interactions, comprehensive proteomic analysis revealed two pivotal transcriptional regulators, the tumor suppressor protein p53 and histone deacetylase 7 (HDAC7) to be potential mechanistic targets

Jakubowicz D, Froy O, Ahrn B et al (2014) Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomized clinical trial