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For example, when activation of endothelial TLR2 induces production of inflammatory mediators and chemoattractants, such as IL-6, granulocyte colony stimulating factor (G-CSF), and IL-8 (Wilhelmsen et al., 2012), which can further immune responses by acting on neighboring microglia and perivascular macrophages

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Sleep fragmentation and the risk of incident Alzheimers disease and cognitive decline in older persons

In a recent conference presentation, a team led by Jonathan Repple, a psychiatry researcher at Goethe University in Frankfurt, Germany, described how they scanned the brains of acutely depressed volunteers and found that they differed structurally from those of a non-depressed control group