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Research suggests that continuous or intermittent medication use yields better long-term outcomes than stopping altogether, especially for people with genetic predispositions to higher appetites or lower metabolic rates

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However, Mounjaro is FDA-approved for managing type 2 diabetes, while Zepbound is approved for helping adults with obesity, or those overweight with at least one weight-related health condition such as hypertension or high cholesterol, in weight management

Both Ozempic and retatrutide (in research settings) require refrigerated storage