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[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Harris I.S., Treloar A.E., Inoue S., Sasaki M., Gorrini C., Lee K.C., Yung K.Y., Brenner D., Knobbe-Thomsen C.B., Cox M.A., et al

Gene Expression Effects GHK-Cu demonstrates powerful effects on gene expression, with studies showing it can modulate expression of hundreds to thousands of genes involved in tissue repair, oxidative stress responses, cell proliferation, protein synthesis, and cellular function

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15,16 PPIs also reduce the size of the acid pocket and increase the pH (from 1 to 4) of its content