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That does not mean you need to panic, but it does mean persistent symptoms should not be brushed off

For instance, fecal microbiota from patients with BD can induce neutrophil activation when transferred to mice, which contributes to the differentiation of pathogenic T cells (65)

As superoxide is subject to efficient dismutation by cellular superoxide dismutases, it is possible that NFT might directly interact with Keap1 to induce the observed release of Nrf2 and its escape from proteasomal degradation