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Due to their genetic similarity to humans and ability to replicate human pathophysiology to a certain extent, mice are commonly used as experimental models 4,5

Snus, which is a type of moist snuff first used in Sweden and Norway, does have an expiration date on its tin cans

While not a perfect analogue, such a system has many of the attributes necessary for a long-term framework for the management of nicotine in society

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A couple of years ago I was reminded about the story by a dear friend