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This work represents one of the first demonstrations of FOXO4-DRI activity in primary human cells, supporting translational relevance beyond the initial mouse model findings

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Additionally, S-Acetyl-L-glutathione has demonstrated potential in inducing apoptosis in some tumor cell lines, suggesting its utility in oxidative stress and cancer therapy

As shave and punch biopsies contain only the central portion of the lesion, the area of interface between the melanocytic lesion and normal skin is absent

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