The gradual dose increase helps reduce side effects, particularly the common digestive issue, when starting treatment
The rest of the field, including Lilly's own Zepbound, tops out around 20% to 22% weight loss
Hyperammonemia in a woman with late-onset ornithine transcarbamylase deficiency
The biological functions of stromal cell-derived factors 1 and 1 (SDF-1 and SDF- 1, CXCL12), macrophage-derived chemokine (MDC, CCL22), interferon-inducible T cell -chemoattractant (ITAC, CXCL11), inflammatory protein-10 (IP10, CXCL10), monokine-induced by gamma interferon (MIG, CXCL9), eotaxin (CCL11), granulocyte chemotactic protein 2 (GCP2, CXCL6), and Gro (CXCL2) have been shown to be substrates for proteolytic modification by DPP4
All these could pose significant financial burdens on the companies involved