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Collectively, these findings consistently indicate that L-citrulline exerts therapeutic benefits across diverse disease models through the enhancement of NO signaling

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Oligodendrocytes also accumulate sphingomyelin and GalCer and C22:0, C24:0 and C24:1 ceramides are found in oligodendrocytes (Hammerschmidt and Brning, 2022) (Figure 1)

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Theres some evidence the supplement may be particularly helpful for people with insulin resistance who have polycystic ovary syndrome (PCOS), a hormonal condition that interferes with periods and the ovaries