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In patients with hepatic encephalopathy, the impaired reaction of cerebral oxyhemoglobin concentration might occur due to astrocyte swelling and dysfunction 42,43,44 because some reports showed that astrocyte controls the regional cerebral blood flow and provides energy sources such as ketone body and carnitine to the neuron 39,41

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Doctors might try changing the dose, suggesting what to eat, or checking if something like food intolerance or another stomach issue is causing the problem

664 Annexin A5 (A5) has anticoagulant and anti-inflammatory biological activities