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Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

This hormone helps control blood glucose levels, insulin production, and feelings of fullness

GLP-1RA and SGLT2 inhibitors, which are currently approved for use in diabetes, have shown early efficacy in NASH, and also have beneficial cardiovascular or renal effects

Superoxide dismutases in the lung and human lung diseases

However, several translational barriers remain, including limited bloodbrain barrier penetration, species differences in pharmacokinetics, and variability in treatment response due to genetic and metabolic factors