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7 The second leading cause is toxic multinodular goiter, in which the nodules become a source of TH independently and do not respond to TSH signaling

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2 Mechanisms of neurodegenerative diseases Neurodegenerative diseases are a group of age-related disorders characterized by highly heterogeneous pathogenesis and clinical manifestations, with progressive loss of vulnerable neurons and gradual decline in brain function ( 2.1 Genetic factors in neurodegenerative diseases Age remains a key risk factor for AD, which predominantly affects the elderly and causes significant burdens on daily living through progressive memory and learning deficits ( Furthermore, recent studies have shown that under stress from ferroptosis inducers, DJ-1 can significantly suppress ferroptosis

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Measurement of oxLDL using E06 antibody showed that: 1) significant elevation of oxLDL in acute coronary syndromes (250), 2) treatment with a statin markedly reduced these levels (253), 3) oxLDL levels are higher in children with familial hypercholesterolemia compared to their siblings (254), and 4) oxLDL levels predict the presence and progression of atherosclerosis and symptomatic cardiovascular disease (255)