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Nogueiras R, Nauck MA, Tschop MH

Lifestyle interventions should prioritize weight loss through dietary modificationsparticularly reducing the intake of high-fat and high-sugar foodsand regular physical activity and the strict avoidance of alcohol due to its adverse impact on lipid metabolism

Instead it's benefits extends to reduction of CV risk

GLP-1 injections mimic a natural hormone that regulates appetite, slows digestion, and helps control blood sugar levels

Example: When parathyroid hormone (PTH) is given orally with N-[38]amino caprylic acid (a transport carrier), it shows positive activity, even though PTH alone is not absorbed