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The three targets are the GLP-1 receptor, the GIP receptor, and the glucagon receptor

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Gastrointestinal symptoms that some patients experience while on GLP-1 therapysuch as nausea, reduced appetite, or altered bowel habitsgenerally resolve as the medication clears from the system, typically within 1-2 weeks for short-acting formulations and within 4-8 weeks for long-acting preparations, corresponding to their elimination timelines

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doi: 10.2337/db06-0558 46 XuFCaoHChenZGuHGuoWLinBet al

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