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Synergism by individual macronutrients explains the marked early GLP-1 and islet hormone responses to mixed meal challenge in mice

Surgery and spinal cord injury Deeply anesthetized (3% isoflurane, ketamine 50 mg/kg b.w.) rats were subjected to laminectomy at lumbar level L2L3, which corresponds to the sacrocaudal spinal cord (S2-Co1) as described previously [42]

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Thus in addition to increasing GLP-1 concentration, recent research shows that it also lowers insulin concentration and stabilizes ghrelin levels