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Additionally, IPI-926, a Hedgehog pathway inhibitor, has been evaluated in head and neck cancer (NCT01255800, Phase I)

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Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class mu glutathione transferases and its role in cellular resistance in rat brain tumor cells Cancer Res 1989 49 : 26212625 Loe DW, Stewart RK, Massey TE, Deeley RG, Cole SP

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