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The metabolic adaptability of Tregs also highlights the complexity of tumor therapy, necessitating simultaneous intervention in metabolic limitations of effector T cells (e.g., glucose competition) and alternative metabolic pathways of Tregs (e.g., lactate utilization) (100)

The gut microbiota at 1 year of age may link exposure to antibiotics and asthma at 5 years, as increased gut microbiota diversity was linked to a 32% lower chance of asthma at 5 years old [13]

580 Alpha-lipoic acid exerts its neuroprotective effects by inhibiting calpain1 activity of and significantly reducing Ca 2+ levels in mouse brain tissue

Liver tissue showed normal architecture with a mildly dilated portal area, and with periportal and perisinusoidal fibrosis compared with the LETO control group

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