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The supplement is recommended for people during weight loss, fat reduction and when working towards a shapely, athletic figure

However, some people report: Different timing of fullness signals Slightly faster gastric emptying (glucagon effect) Less bloating compared to tirzepatide If you had significant GI issues on tirzepatide, retatrutide is often better tolerated once you're past the first week

Diabetologia 67(Suppl 1):abstract 81 Ali A, Khan D, Dubey V, Tarasov AI, Flatt PR, Irwin N (2024) Comparative effects of GLP-1 and GLP-2 on beta-cell function, glucose homeostasis and appetite regulation

G., and Luderer, U

Zheng et al., 2019