When the fat beneath the skin disappears quickly, and collagen production can't keep up, the result can be loose skin
doi: 10.1002/14651858.CD011031.pub3 13 BonavinaGTaylorHS
Contact your healthcare provider promptly if you experience any of the following after injection: significant swelling or hardness at the injection site that does not resolve within 48 hours, redness that expands beyond two inches from the injection point, warmth or heat radiating from the injection site combined with pain, any discharge from the injection site including pus or cloudy fluid, fever following injection, severe allergic reaction signs including hives or difficulty breathing, or persistent pain that intensifies rather than improving over 24 hours
The effects were generally small, the studies varied in design, and spices were not tested in isolation from other dietary and lifestyle factors, so this doesnt mean spices alone cause weight loss
Besides, the NMN administration also exerts a pleiotropic effect on acute heart failure and renal injury
