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In PD, where anorexia and delayed gastric emptying are already common due to autonomic dysfunction, this may exacerbate nutritional deficiencies
Substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders (heart attack, heart failure, ischemic stroke, and hemorrhagic stroke, pulmonary embolism, pulmonary hypertension, coagulopathy and clotting disorders) chronic kidney disease, COPD, pneumonia, liver failure, inflammatory bowel disease, liver cancer) all significantly declined
Methods Ethics statement The study was conducted in compliance with the guidelines of the Institutional Animal Care and Use Committee of Shanghai Tenth Peoples Hospital (approval ID, SHDSYY-2023-P0011)
Key Takeaways Standard aod 9604 dosage: 300mcg/day subcutaneous, fasted AM Phase 2 clinical data showed 1mg/day as optimal most research protocols run 300500mcg 5mg vial + 2.5mL BAC water = 2,000mcg/mL
