View on PubMed [PubMed] Pentadecapeptide BPC 157 Counteracts L-NAME-Induced Catalepsy in Rat Models (2021) Controlled rat study in which BPC-157 counteracted dopaminergic and NMDA-receptor-related motor disturbances and haloperidol-induced catalepsy while modulating the nitric oxide system
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In a model of non-ischemic HF in dogs (tachycardiomyopathy induced by pacemakers), IV infusion of GLP-1 increases left ventricular (LV) contractility (LV dP/dt increased by 98%, stroke volume by 102%, and cardiac output by 57%) and decreases LV end-diastolic pressure, heart rate, and systemic vascular resistance