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It also investigated the effect of removing beta-carotene from the supplement, since supplementation of this vitamin A precursor has been associated with increased risk of certain cancers among smokers and previous smokers

Even if its safe in small doses, we have no data about what happens at higher doses

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Scott CP, Abel-Santos E, Wall M, Wahnon DC, Benkovic SJ (1999) Production of cyclic peptides and proteins in vivo

A comparative study of data-independent acquisition and data-dependent acquisition in liquid chromatography-mass spectrometry-based untargeted metabolomics analysis of Panax genus sample