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Galactose modified prodrugs Duocarmycin Senescent cells are characterized by high levels of (SA--Galactosidase) implying that generation of prodrugs combining a cytotoxic compound linked to a cleavable galactose part should be preferentially processed by those cells
Nakano M, Murayama Y, Hu L, Ikemoto K, Uetake T, Sakatani K
doi: 10.1186/s12944-018-0797-2 133 JavadiFAhmadzadehAEghtesadiSAryaeianNZabihiyeganehMRahimi ForoushaniAet al
By treating this process with the seriousness it deserves, you ensure that the data you generate is built on a foundation of stability, accuracy, and purity
Life Sci 185:5362
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