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[27] However, 3% to 6% of people given intravenous acetylcysteine show a severe, anaphylaxis-like allergic reaction, which may include extreme breathing difficulty (due to bronchospasm), a decrease in blood pressure, rash, angioedema, and sometimes also nausea and vomiting

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For DPP-4 inhibitors the IRRs were likewise lower in both periods, compared to the pretreatment period (Fig