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Most research protocols observe significant GH elevation for 60-120 minutes post-administration, with gradual decline thereafter as the body metabolises the compound

Materials and Methods Animals Adult male Wistar rats (250320 g), from the Department of Pharmacology vivarium (Facultad de Ciencias Qumicas, Universidad Nacional de Crdoba, Argentina), were randomly housed in groups of three, one week before the beginning of the experimental protocol

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UA Degradation Activity of PDA@Pt Pt NPs serve as efficient mimics of uricase in the oxidation process of UA, catalyzing its degradation into more soluble substances without generating H 2 O 2 [18]