Plus, because B12 vitamin is bound to amino acids (found in protein foods) and is only released when certain enzymes and stomach acids are present, its possible to consume enough but still remain somewhat deficient
[3] A 2018 follow-up study further characterized 5-Amino-1MQ in cell-based assays and reported the following selectivity profile against other methyltransferases and related enzymes at concentrations up to 600 M: no detectable inhibition of DNMT1, PRMT3, or NAMPT
People with Digestive Issues : Individuals with digestive conditions such as Crohns disease, celiac disease, or irritable bowel syndrome (IBS) may have difficulty absorbing B12 from food
Helps regulate mood, sleep, and metabolism Because B12 is water-soluble and some people dont absorb it well through digestion, direct intramuscular injection ensures full availability, no gut absorption barriers, no wasted nutrients
Probably not a great idea, though AOD-9604 has no known hormonal suppression effects