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doi: 10.2307/2683903 43 AustinPC

Lu Journal: Antibiotics Journal ranking: Q1 Key takeaways: Antimicrobial peptides show potential as therapeutic drugs, but their stability and toxicity require understanding their mechanisms and effects on the human body

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These modifications were designed to: Increase molecular stability Reduce rapid degradation Extend systemic exposure Support prolonged receptor engagement These approaches are commonly used throughout peptide research when investigators seek to improve pharmacokinetic characteristics

Disruptions in those processes lead to increased amounts of reactive oxygen species (ROS) that can cause oxidative stress