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It acts as a growth hormone (GH) secretagogue stimulating levels of GH and insulin-like growth factor 1 (IGF-1), while preserving GH pulsatility

The two peptides operate through largely complementary rather than overlapping mechanisms, which suggests a potentially additive or even synergistic effect in tissue repair models

Gupta S, Aggarwal S, Rashanravan B, Lee T

Similarly, copper peptides and retinol may cause irritation if used together without proper spacing

Whilst many symptoms improve with appropriate B12 treatment, not all resolve completely, especially if neurological damage was severe or prolonged before treatment commenced