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Wang H, Fan S, Zhan Y, Xu Y, Du Y, Luo J, et al

doi:10.1002/nbm.4854 127

Comprehensive toxicology evaluations reveal that the compound does not affect food intake, body temperature regulation, or basic physiological parameters at effective doses in animal models, indicating that its metabolic effects occur through specific pathway modulation rather than general physiological disruption

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Vitamin B12 deficiency may contribute to neurological symptoms such as numbness, tingling, reduced sensation, and peripheral neuropathy, as well as megaloblastic anemia caused by impaired red blood cell production