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The possible cardioprotective mechanisms of GLP-1 RAs include reducing epicardial fat tissue thickness, preventing activation of the reninangiotensinaldosterone system, improving myocardial energy metabolism, reducing systemic inflammation and cardiac oxidative stress, and delaying the progression of atherosclerosis
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The gene expression data is a hypothesis generator, not a clinical endpoint
To view or add a comment, sign in More Relevant Posts Chief Medical Officer Florencia Halperin shares her thoughts on the ATTAIN-1 trial, whose results were published in the New England Journal of Medicine this week
doi: 10.2337/db13-1087 105 TurecekPLBossardMJSchoetensFIvensIA
Consistent with our BrdU/NeuN findings, males had a greater percentage of BrdU/DCX-ir cells expressing type-C morphology compared with females at 2w in the dorsal DG (a priori: p = 0.017, Cohens d = 1.84
