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People with uncontrolled high blood pressure, certain heart conditions, glaucoma, hyperthyroidism, or a history of substance misuse may need a different option

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If a social event feels too high-risk early in recovery, it is entirely reasonable to decline and suggest an alternative activity

If side effects like nausea or fatigue appear, doctors may pause or lower the dose temporarily before slowly increasing it again

It could explain why COVID-19 in these people has a more severe course, with higher vulnerability to cytokine storms and fulminant multi-organ failure