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27 Immunofluorescence staining showed a reduction in the expression levels of HIF1 and phosphorylated STAT3 (p-STAT3) in the medial layer of pulmonary arteries in METH-treated LCN2 / mice compared with METH-treated WT mice (Figure 5A and 5B)

Given the downstream consequences of senescent cells, even when efficiently cleared by microglia, eliminating them with therapeutic interventions may potentially mitigate their abundance, reduce inflammation, and alter disease progression

The experimental framework through which studies may reliably assess the ameliorative potential of the tested compound is available in Table S3

Diarrhea: This side effect is like a sudden rainstorm that can dampen any Hollywood premiere, but patients can manage it by staying hydrated and eating a balanced diet that's high in fiber

Consistency is key to seeing results, as skin regeneration is a gradual process