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The list of research needs to inform FDA and ENDS regulation will be prioritized with respect to: --research to gather information of most importance for the regulation of ENDS to protect the population health

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They may be marketed in ways that put the public health at risk and should especially be kept out of reach of children and pets

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Most experts believe there is harm linked to the use of e-cigarettes, but as no long-term data exists on the development of disease across a lifetime, it is not possible to conclude how harmful e-cigarettes are at this stage