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Loss of appetite is uncommon and may indicate pancreatitis

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It also enhances the expression of type IIa muscle fiberspecific genes, including MyHC I, Troponin I1 (TNNI1), and Troponin C1 (TNNC1), and inhibits the expression of type IIb muscle fiberspecific genes ( MyHC IIa , MyHC IIx , MyHC IIb ) by binding to various transcription factors such as NRF1 and MEF2 (117)

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