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Results of IVIP T-cell assays As previously mentioned, the low incidence of observed clinical immunogenicity associated with TPT may be attributed to (a) TPT being derived from the N-terminus of human PTH (an endogenous peptide) and/or (b) due to the presence of a potential Treg epitope in the N-terminus that is cross-conserved with -tubulin and other self-proteins

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Kheirbek, 2015)

A second study compared the occurrence of FG in patients treated with SGLT2 inhibitors (15.0 per 100,000 person-years) vs DPP4 inhibitors (9.7 per 100 000 person-years) in men 65 years and older who have T2DM using large data bases (216)