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b , Gene set enrichment plots comparing DNMT3A R882 versus DNMT3A WT CD34 + HSPCs from individuals with CH using the publicly available GSE158067 gene expression dataset and analyzed as pseudobulk populations

The lungs, kidneys, and brain also depend heavily on adequate glutathione levels for optimal function

Kassel R, Sprietsma L, Rudnick DA

Therefore, Trx may have a neuroprotective function in individuals suffering from acute ischemic stroke, and serum Trx levels are novel diagnostic and prognostic indicators that are also closely related to the severity of intracranial hemorrhage and long-term mortality

62 Alcohol use exacerbates liver injury in both infections: 26.5% of CHB patients report excessive alcohol consumption, rising to 35.6 and 41.8% in hepatitis B virus (HBV)-related cirrhosis and liver cancer patients, respectively, 114 while alcohol consumption synergistically exacerbates hepatitis C virus (HCV)-related liver damage