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Physiol Rev 91:14471531 Schoeman EM, van der Westhuizen FH, Erasmus E et al (2017) Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome

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Estimates suggest that depression affects 9.3%25% of chronic disease patients (Ma et al., 2021

PARPs are most commonly known for DNA repair, although they also function in transcription, cell cycle regulation, and proteasome regulation 7

doi:10.1021/jm070461w