And anecdotal reports have suggested some patients are reporting changes in mood, including anxiety, depression and suicidal thoughts, according to a Healthline article describing what some people are calling Ozempic personality. On the other hand, researchers recently published an analysis in JAMA Internal Medicine which concluded that semaglutide did not increase the risk of depression or suicidal ideation
Intestinal L cells-derived GLP-1 induce insulin secretion in response to meal intake
Dr Kristopher Welsh Medical Director, Yorkshire Wellness Clinic
Hector Perez, MD, a board certified bariatric surgeon at Renew Bariatrics and an advisor at BestSurgeons.com, who was not involved in the study, said that while the risk for ION is worth monitoring, the study is very small
It is given as a weekly injection and has been shown in clinical trials to produce significant weight loss over months of treatment