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A total of 10 highly trained men completed measures of serum EPO concentration, total hemoglobin mass (via carbon monoxide rebreathing), hemoglobin concentration, and reticulocytes before and after 7 days of supplementation with 1800 mg/day of NAC or placebo in a repeated measures, cross-over design with washout
Document symptom timing, check blood glucose during episodes, and discuss whether dose adjustment, symptomatic treatment, or mental health referral is appropriate
Crackers, toast, bananas, rice, and broth are your friends during the first two weeks
These setbacks demonstrate that while GLP-1 RAs show promising biomarker effects in the brain, translating them into meaningful clinical outcomes in neurodegeneration remains an unresolved challenge
