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published in Molecular Brain confirmed endogenous MGF expression in neurogenic brain areas with age-dependent decline, and that transgenic MGF overexpression significantly increased BrdU+ proliferative cell counts in the dentate gyrus and subventricular zone of the hippocampus establishing MGF as a neurogenesis-promoting factor in ageing brain biology and directly relevant to PEG-MGF neurogenesis and neuroprotection research applications

Gelderblom and J

From the DNA sequence of this cloned gene one could i) predict the final amino acid protein sequence ii) produce large amounts of recombinant protein in the lab and iii) more easily study protein functionby transfecting the recombinant gene into cells or administering exogenous protein to tissue cultures or animals

10.1007/s11883-017-0678-6 14

10.3389/fimmu.2020.01323 29 CamargoL