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Additionally, OLE is able to neuroprotect from death PC12 cells exposed to 6-OHDA by reducing mitochondrial production of ROS and favoring autophagy [145]
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Then substrate A (50 l) and substrate B (50 l) were added to each well, gently mixed, and incubated for 15 min at 37 C in dark
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The study was based only on data from the published literature, did not allow for prospective or randomized controlled trials, and did not explore the direct associations between drug penetration ratios and adverse fetal or neonatal outcomes
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